A think tank for accelerating scientific, technological, and industrial progress

Spotlight research
Emerging Technology
Should the US Sell Blackwell Chips to China?
Assessing the impacts of exporting the NVIDIA B30A AI chip
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October 25th 2025
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Emerging Technology
How to Implement an Operation Warp Speed for Rare Earths
A coordinated, whole-of-government effort to secure America’s rare earth supply chain
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October 21st 2025
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High-Skilled Immigration
The “Wage Level” Mirage
How DHS’s H-1B proposal could help outsourcers and hurt US-trained talent
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September 24th 2025
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Metascience
Indirect Cost Recovery and American Innovation: Context and Ideas for Reform
How the government covers indirect costs directly affects scientific innovation
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July 24th 2025
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Read more recent publications

Metascience
How Much Should We Spend on Scientific Replication?
A data-driven framework for targeting replication funding where it matters most
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October 31st 2025
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Emerging Technology
Unlocking a Million Times More Data for AI
How a new ARPANET-style program could solve the data accessibility problem
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September 23rd 2025
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Metascience
American Science Should Take a Lot More Risks
Scientific efficiency isn’t primarily about the dollars we could save; it’s about the breakthroughs we could be missing
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August 29th 2025
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Emerging Technology
Preparing for Launch
An introduction to The Launch Sequence: Why shaping AI progress matters, and how to go about it
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August 11th 2025
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Emerging Technology
Teaching AI How Science Actually Works
How block-grant labs can generate the real-world data AI needs to do science
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August 11th 2025
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Emerging Technology
Using X-Labs to Unleash AI-Driven Scientific Breakthroughs
How to adapt our science funding mechanisms to the unique infrastructure needs of large-scale AI projects
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August 11th 2025
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Emerging Technology
The Replication Engine
How to build automated replication infrastructure for better, faster science
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August 11th 2025
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Emerging Technology
Benchmarking for Breakthroughs
How to incentivize AI for national priorities through a strategic challenge and evaluations program
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August 11th 2025
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Emerging Technology
Scaling Materials Discovery with Self-Driving Labs
How to close the gap between AI-guided material design and real-world validation
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August 11th 2025
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Emerging Technology
A Million-Peptide Database to Defeat Antibiotic Resistance
How to build a large peptides database to train the AlphaFold for new antibiotics
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August 11th 2025
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Emerging Technology
Faster AI Diffusion Through Hardware-Based Verification
How to use privacy-preserving verification in the AI hardware stack to build trust and limit misuse
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August 11th 2025
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Emerging Technology
Operation Patchlight
How to leverage advanced AI to give defenders an asymmetric advantage in cybersecurity
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August 11th 2025
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